Experimental determination of pesticide processing factors during extraction of seed oils

ABSTRACT

Processing Factors (PFs) reflect the concentration or dilution of pesticide residues resulting from food processing. PFs are key elements to demonstrate the compliance of processed foods with Maximum residue levels (MRLs) as set by Regulation 396/2005. While efforts have been made by the European Food Safety Authority (EFSA) and by national authorities to compile PFs from processing studies, such PFs are not available for all pesticides/processed product combinations. The EU vegetable oil and proteinmeal industry association (FEDIOL) has therefore developed a theoretical approach to approximate MRLs in crude vegetable oils and fats, based on the partition coefficient (log P_ow) of the pesticides and on the oil content of the raw materials. To substantiate this approach, a pilot-scale processing study was initiated with rapeseeds spiked with selected pesticides and the experimental PFs for these pesticides determined. The aims of this study were (i) to study the reliability of pilot-scale conditions for PF determination and (ii) to assess the experimental PFs obtained in comparison to the theoretical PFs proposed by FEDIOL. This study demonstrated that production yields obtained for crude oil and meal in this processing study are similar to those in industrial processes even if differences were observed in the individual production steps (mechanical or solvent extraction steps). The experimental PFs obtained confirmed that the chosen fat-soluble pesticides did concentrate in the oil fraction. For metalaxyl-M having a log P_ow lower than 3, a partitioning between the oil and the meal was observed, as expected. By comparing the experimental PFs and theoretical PFs, it can be concluded that the FEDIOL approach can be recommended as a suitable tool when PFs derived from specific processing studies are missing. Similar studies on pesticides with wider ranges of log P_ow are required in order to complete our conclusions on default PFs for vegetable oils.     

破囊壶菌发酵生产DHA的研究进展

二十二碳六烯酸（DHA）是一种非常重要的多不饱和脂肪酸，能参与人及动物体内多个生理过程。破囊壶菌具有生长迅速、细胞内DHA含量高的特点，是工业化生产DHA的潜力菌。本文主要介绍破囊壶菌DHA代谢通路、影响破囊壶菌生产DHA的因素以及破囊壶菌中试发酵的研究现状。首先，对破囊壶菌合成DHA的两个代谢途径，即脂肪酸合成酶（fatty acid synthesis pathway，FAS）途径和聚酮合酶（polyketide synthesis pathway，PKS）途径进行总结和描述；其次，对影响破囊壶菌发酵生产DHA的三个主要因素（碳氮源、溶氧和温度）进行综述；随后，阐述了破囊壶菌发酵生产DHA的中试放大工艺的研究现状；最后，提出破囊壶菌发酵生产DHA过程中存在的问题，并指出进一步分离获得优质的破囊壶菌菌株、对其代谢途径和关键酶的研究以及中试放大工艺的研究是下一步研究的重点。通过对上述一系列问题进行综述，旨在为利用破囊壶菌工业化生产DHA提供一定的参考。     

Health risk assessment of chlorpyrifos inhalation exposure among chilli-growing farmers in Na-Krasaeng Sub-District,Det Udom District,Ubon Ratchathani Province,Thailand

The paper reports a health risk assessment of pesticide exposure among chilli-growing farmers living in Na-Krasaeng Sub-District, Det Udom District, Ubon Ratchathani Province, Thailand. Personal air samples were collected from 46 participants spraying pesticide. These samples were analysed to investigate the farmers’ exposure by inhalation of the organophosphate, chlorpyrifos, which is the predominant pesticide used in the study area. The potential health risk of the farmers through inhalation was estimated by calculating the Hazard Quotient (HQ). The results showed that chlorpyrifos concentrations in inhaled air samples from the farmers ranged from less than the limit of detection, <LOD, to 0.041 mg/m3 with an average of 0.0072 mg/m3. Average daily doses (ADD) of exposure were calculated to be in the range 0–0.007 mg/kg/day with a mean value of 0.0014 mg/kg/day. The estimated risk quotient was 0 to 2.35 and the mean value was 0.84. Accordingly, the chilli-growing farmers were not considered to be a population at risk (mean value of HQ ≤ 1). But, the estimated risk of 17.38% of the study population was higher than the acceptable level (HQ > 1). This indicated that some participants were considered as an individual risk which should be of concern.     

水电站大型竖井施工安全风险控制措施研究

竖井是大型水电工程中广泛采用的重要建筑物,但竖井的传统施工方法存在施工程序复杂、人工劳动强度大、施工效率不高等特点,同时还存在较大的安全风险。通过对杨房沟水电站大型竖井施工过程的研究,总结出精细化控制爆破、小溜渣井施工方式,同时也设计了一套用于运输的综合提升系统。采用上述创新方法不仅减少了繁琐的施工程序,降低了安全施工风险,而且大量采用机械化手段进一步提高了施工效率,确保了该工程竖井施工的安全风险可控。相关措施可为类似工程的竖井施工提供较好的借鉴作用。     

Airborne spread of expiratory droplet nuclei between the occupants of indoor environments: A review

This article reviews past studies of airborne transmission between occupants in indoor environments, focusing on the spread of expiratory droplet nuclei from mouth/nose to mouth/nose for non‐specific diseases. Special attention is paid to summarizing what is known about the influential factors, the inappropriate simplifications of the thermofluid boundary conditions of thermal manikins, the challenges facing the available experimental techniques, and the limitations of available evaluation methods. Secondary issues are highlighted, and some new ways to improve our understanding of airborne transmission indoors are provided. The characteristics of airborne spread of expiratory droplet nuclei between occupants, which are influenced correlatively by both environmental and personal factors, were widely revealed under steady‐state conditions. Owing to the different boundary conditions used, some inconsistent findings on specific influential factors have been published. The available instrumentation was too slow to provide accurate concentration profiles for time‐dependent evaluations of events with obvious time characteristics, while computational fluid dynamics (CFD) studies were mainly performed in the framework of inherently steady Reynolds‐averaged Navier‐Stokes modeling. Future research needs in 3 areas are identified: the importance of the direction of indoor airflow patterns, the dynamics of airborne transmission, and the application of CFD simulations.     

Effects of yoghurt butter oils on rat plasma lipids,haematology and liver histology parameters in a 150‐day study

Although yoghurt butter oil as a fermented dairy product is widely consumed in several countries, its metabolic effects have not been fully elucidated. In this study, male Wistar rats were treated with standard diet, standard diet enriched with 10% or 20% (W/W) of either cow yoghurt butter oil (CYBO), sheep yoghurt butter oil (SYBO) or cottonseed oil (COT) for 20 weeks. Treatment of rats with CYBO or SYBO (at both concentrations) did not significantly influence haematological parameters, plasma lipids and liver histological structure. However, in contrast to popular belief, COT treatment at the higher dose induced leukocytosis, dyslipidaemia and liver steatosis.     

基于峰谷分时电价的虚拟电厂日前申报及运行优化

鉴于分布式能源的出力性质为间歇性和波动性,影响电网安全高效运行,而虚拟电厂可解决此问题。对虚拟电厂进行申报-调度两阶段建模,以包含分布式电源(光电、风电和燃气轮机)和储能系统(储能电池)两大类分布式能源的虚拟电厂为例,基于光照强度及风速等不确定因素,研究峰谷分时电价下日前市场虚拟电厂的出力申报和运行调度策略并利用风险价值模型进行风险管理。结果表明,申报出力时,当电价激励足够高时储能电池方会参与出力,成功起到削峰填谷的作用;运行调度时,平衡出力偏差方面,储能电池发挥主要作用,且虚拟电厂运行调度策略具有一定的经济效益。     

计及风险规避的电力零售商平衡市场交易模型

由于新能源出力以及终端负荷需求的不确定性,电力零售商在日前市场的竞标电量与实时市场的购买电量之间存在不平衡而产生惩罚成本风险。引入用户侧可控负荷作为平衡资源参与市场交易,提出了一种风险规避程度指标,以此来度量交易前后电量偏差程度,以信息熵度量残差序列离散程度计算风险规避程度指标。以电力零售商运行收益、用户需求响应满意度以及风险规避程度最大为目标建立多目标风险规避模型,采用自适应权重粒子群算法进行模型求解。通过算例表明,所提出的模型从电网-电力零售商-用户多个角度去考虑电力零售商参与平衡市场交易策略,能够有效提高电力零售商的运行效益以及用户满意度,同时可以提高电力市场管理的可靠性与安全性。     

地勘单位转制后税务风险识别与控制

结合“减税降费”的政策背景,以陕西省某转制地勘单位为例,引入风险控制相关理论并应用层次分析法,构建了税务风险评估指标体系,对转制地勘单位面临的税务风险进行了识别、分析、评估。研究结果表明:针对不同的税收类型,应着重关注不同方面的风险,排序前6位的风险依次为企业所得税扣除类风险、增值税决策环节风险、增值税销售环节风险、房产税计税依据风险、企业所得税税收优惠类风险、增值税采购环节风险;并对上述风险的控制机制进行了分析,从企业管控、政策优化两方面分别提出了相关对策和建议。